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. 2008 Aug 29;295(4):H1772–H1779. doi: 10.1152/ajpheart.216.2008

Fig. 4.

Fig. 4.

Cumulative effects of inhibition of NTS and inhibition or blockade of glutamatergic inputs to the CVLM on SNA and mean AP. Inhibition of the NTS by bilateral microinjection of Mus significantly increased SNA and AP in all rats. Subsequent inhibition of the CVLM by bilateral microinjection of Mus (n = 6) significantly increased SNA (A) and mean AP (B) above the levels achieved by inhibition of the NTS alone. Likewise, after inhibition of the NTS, antagonism of glutamatergic receptors in the CVLM (n = 7) by bilateral microinjection of kynurenate (Kyn) produced an additional increase in SNA (C) and mean AP (D). *P < 0.05, significant increase from 100% baseline; †P < 0.05, significantly different from SNA and mean AP values after inhibition of the NTS.