Table 3.
Follow-up after diagnosis of APRT deficiency
| Parameter | Value |
|---|---|
| Follow-up duration (months; median [IQR]) | 74 (14 to 112) |
| Allopurinol therapy (n [%]) | 35 (87.5) |
| Allopurinol dosage (median [IQR]) | |
| adults (n = 22; mg/d) | 300 (200 to 300) |
| children (n = 11; mg/kg per d) | 10 (9 to 10) |
| Stone recurrence (n [%]) | 6 (15.0) |
| treated by allopurinol (n = 35) | 5 (14.3) |
| untreated (n = 5) | 1 (20.0) |
| Urologic procedures (n [%]) | |
| 0 | 30 (75.0) |
| 1 to 2 | 8 (20.0) |
| >3 | 2 (5.0) |
| Type of urologic procedures (n [%]) | |
| extracorporeal shock waves | 7 (17.5) |
| ureteroscopy | 3 (7.5) |
| percutaneous nephrolithotomy | 1 (2.5) |
| surgery | 2 (5.0) |
| nephrectomy | 2 (5.0) |
| Reaching ESRD during follow-up (n [%]) | 2 (5.0) |
| Renal transplantation during follow-up (n [%]) | 2 (5.0) |
| Total ESRD before or during follow-up (n [%]) | 8 (20.0) |
Data regarding follow-up for the 40 patients described in Table 2 are provided here.