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. 2010 Apr;21(4):654–665. doi: 10.1681/ASN.2009020182

Figure 10.

Figure 10.

Serum IgM levels varied after IRI. (A) In the control (wild-type) mice that underwent renal IRI, serum samples obtained on day 28 after renal IRI contained significantly higher IgM compared with serum samples obtained on days 0 and 10 (n = 5 to 12 per group). *P < 0.05 versus both days 0 and 10. (B) On day 28 after renal IRI, serum IgM was not detected in μMT mice. B cell–transferred μMT mice had significantly higher IgM in their serum than μMT mice but a comparable level of IgM to control mice (n = 7 to 12 per group). *P < 0.001 versus control; †P < 0.001 versus μMT. (C) On day 28 after renal IRI, MR16-1–treated mice revealed a significantly reduced level of serum IgM compared with control IgG-treated mice (n = 6 per group). *P < 0.01 versus control IgG.