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. Author manuscript; available in PMC: 2010 Mar 23.

Published in final edited form as: Circulation. 2008 Apr 14;117(17):2270–2278. doi: 10.1161/CIRCULATIONAHA.107.741512

Table 2.

Relations Between Markers of Endothelial Reactivity, Inflammation, and Oxidative Stress and Severity of OSA

		AHI, Events per h of Sleep
	n	Tertile 1, 0 (0–4)	Tertile 2, 10 (6–20)	Tertile 3, 52 (21–109)	P for Trend
eNOS, au	45	0.66 (0.09)	0.34 (0.09)^*	0.11 (0.10)^*^†	0.001
P-eNOS, au	45	0.54 (0.07)	0.01 (0.07)^*	0.02 (0.07)^*	0.001
Nitrotyrosine, au	45	0.24 (0.24)	1.39 (0.25)^*	1.83 (0.27)^*	0.001
COX-2, au	45	0 (0.33)	0.75 (0.31)^*	0.92 (0.33)^*	0.007
iNOS, au	45	0.17 (0.10)	0.16 (0.10)	0.43 (0.11)^†	0.047
FMD, %	37	9.6 (1.0)	4.3 (1.1)^*	3.5 (1.3)^*	0.001
EPCs, %	37	0.05 (0.01)	0.01 (0.01)^*	0.0 (0.01)^*	0.001

au indicates arbitrary units. Data are presented as mean (SE) or median (range) adjusted for age, gender, and BMI.

^*

P<0.05 vs tertile 1 (control subjects)

^†

P<0.05 vs tertile 2.