Table 4.
Crude and adjusted correlations between objective measures of sleep and biomarkers
| Percent sleep |
Number of awakenings |
Mean duration of awakenings |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| all | CGR | CTR | p | all | CGR | CTR | p | all | CGR | CTR | p | |
| IL-6 | −0.24∗∗ | −0.29∗∗ | −0.10 | 0.288 | 0.10 | 0.15 | 0.01 | 0.457 | 0.26∗∗ | 0.26∗ | 0.16 | 0.597 |
| −0.14 | −0.22∗ | 0.15 | 0.043 | 0.08 | 0.16 | −0.14 | 0.099 | 0.14 | 0.14 | 0.04 | 0.599 | |
| CRP | −0.12 | −0.18+ | 0.03 | 0.265 | 0.02 | 0.12 | −0.22 | 0.066 | 0.13 | 0.09 | 0.19 | 0.598 |
| −0.07 | −0.19+ | 0.22 | 0.028 | 0.03 | 0.15 | −0.19 | 0.066 | 0.08 | 0.10 | −0.08 | 0.345 | |
| D-dimer | −0.19∗ | −0.20+ | 0.02 | 0.221 | −0.01 | −0.03 | 0.02 | 0.786 | 0.24∗∗ | 0.28∗∗ | −0.14 | 0.022 |
| −0.08 | −0.11 | 0.09 | 0.281 | −0.01 | −0.03 | −0.07 | 0.841 | 0.05 | 0.10 | −0.16 | 0.159 | |
| VWF | −0.04 | −0.13 | 0.06 | 0.281 | 0.19∗ | 0.26∗ | 0.06 | 0.254 | −0.09 | −0.05 | −0.10 | 0.770 |
| <–0.01 | −0.11 | 0.04 | 0.410 | 0.17+ | 0.27∗ | 0.08 | 0.282 | −0.14+ | −0.11 | −0.08 | 0.842 | |
The columns show the bivariate (upper row) and adjusted (lower row) correlation coefficients with significance level for all participants, caregivers (CGR) and controls (CTR), and the p value for the comparison of the strength of the correlation coefficients between caregivers and controls. See table 3 footnotes for statistical adjustments of individual biomarkers.
+
p < 0.10,
∗
p < 0.05,
∗∗
p < 0.01.