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. Author manuscript; available in PMC: 2010 Mar 25.
Published in final edited form as: Oncogene. 2009 Aug 31;28(44):3866–3879. doi: 10.1038/onc.2009.257

Figure 4. Inhibition of in vitro induction of angiogenesis by BMP6.

Figure 4

Inhibition of endothelial cell growth by BMP6 in the AngioKit model. Immunostaining with monoclonal anti-CD31 antibody. (A) Shown are medium control (RPMI-1640), positive control (vascular endothelial growth factor), negative control (suramin) and BMP6 in concentrations of 4, 0.8, 0.16 and 0.032 μg/ml, respectively. Original magnification ×40. (B) Boxplot summarizing the CD31 ELISA results. BMP6 significantly inhibits tubule formation down to the level of the negative control.