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. 2010 Mar 24;5(3):e9846. doi: 10.1371/journal.pone.0009846

Figure 8. Time course of fluorescence-positive cells in Cre-activated NSC and NSK cells.

Figure 8

Seven days after NSC and NSK cells were stimulated with OHT to activate MerCreMer, the culture was split into two: one with continued Cre activation (square) and the other without OHT to terminate Cre activation (triangle). Frequencies of fluorescence-positive cells at the indicated time points were measured by flow cytometry and plotted for NSC (inverted loxP sites with a 1.1-Mb interval) trans-targeted cells (A) and cis-targeted cells (B), and NSK (direct loxP sites with a 1.1-Mb interval) trans-targeted cells (C) and cis-targeted cells (D).