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. 2010 Mar 24;5(3):e9846. doi: 10.1371/journal.pone.0009846

Table 2. Targeting configuration of NSC cells with loxP sites spanning 1.1 Mb in the opposite direction.

Targeting configuration Clone No. of metaphase Colocalization Non-colocalization Frequency of fluorescence-positive cells
cis NSC27 8 8 0 1.0×10−2
NSC71 8 8 0 8.2×10−3
NSC130 8 7 1 9.6×10−3
mean frequency (mean ± standard deviation) 9.3±0.9×10−3
trans NSC94 16 1 15 8.8×10−5
NSC169 8 0 8 7.7×10−5
mean frequency (mean) 8.3×10−5

The numbers of metaphases analyzed and those which exhibited colocalization or non-colocalization of signals by Site1 and Site2 probes are shown with frequencies of double-positive cells after 7 days of OHT stimulation.