Skip to main content
. Author manuscript; available in PMC: 2011 May 14.
Published in final edited form as: Mol Cell Endocrinol. 2010 Feb 6;320(1-2):153–161. doi: 10.1016/j.mce.2010.02.005

Figure 7.

Figure 7

The effect of actinomycin D (Act D; 4 μM) and P4 (1 μM) on SIGC apoptosis (A). In panel B, the effect of PGRMC1 siRNA and P4 on endogenous levels of PGRMC1 mRNA is shown. In panels A and B the * indicates a value that is significantly different (p < 0.05) from control (no P4 group). The effects of PGRMC1 siRNA treatment of the expression profile of various apoptosis-related genes is shown in panel C. The mRNA levels of both endogenous PGRMC1 and apoptosis-related genes were assessed by real-time PCR and shown as a percentage change from scramble control values. The values are means (± standard error) of three experiments. Genes associated with the induction of apoptosis are shown in red and the anti-apoptotic genes shown in green.