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. Author manuscript; available in PMC: 2011 May 10.
Published in final edited form as: Virology. 2010 Jan 25;400(2):164–174. doi: 10.1016/j.virol.2009.12.019

Figure 7. Correlation between neutralization sensitivity and genetic characteristics of the envelope.

Figure 7

Neutralization of maternal (○) and infant (Δ) variants was performed with either maternal plasma (A and C) or pooled plasma (B and D). The IC50 was defined as the dilution of plasma that causes 50% inhibition of virus infection. Amino acid lengths and PNGS in Env V1-V5 region of the mother and infant variants were calculated. The coefficient r and P values were generated using Spearman’s correlation test.