Fig. 3.

Effect of MMP-2 on [Ca²⁺]_e-contraction relationship. IVC segments incubated in 0 Ca²⁺ Krebs were either nontreated (A) or treated with MMP-2 (1 μg/ml) for 10 min (B). After eliciting a transient Phe contraction in 0 Ca²⁺ Krebs, increasing concentrations of CaCl₂ were added, the Ca²⁺-dependent contraction was measured and the [Ca²⁺]_e-contraction relationship was constructed (C). Data represent means±SEM of 4 measurements.

* Statistically significant p<0.05