Table 1.
Dex-mediated Killing of Cell Lines And Patient Samples (LCS*)
| Cell Line or Patient Sample Time of Treatment (Hours) | 48 | 72 |
|---|---|---|
| 697 | 4.2% | 1.6% |
| CEM-C7 | 85.8% | 22.2% |
| CEM-C1 | 92.9% | 95.3% |
| IM-9 | 99.1% | 98.4% |
| **TALL1 | 22.1% | - |
| **TALL2 | - | 34.9% |
| **TALL3 | - | 10.2% |
| **TALL4 | - | 18.2% |
*
Leukemic Cell Survival was calculated as described in Materials and Methods
**
To insure a clear result, instead of analyzing the LCS after 48 hours of Dex-treatment of the patient samples (as was done initially), it was decided to use 72 hours of treatment to assay sensitivity to steroid-mediated cell death.