Fig. 4.

Effect of storage temperature on the vaccines’ capacity to induce antibody responses. Pooled sera of each group of mice immunized with liquid or freeze-dried WIV vaccine, which had been stored for 3 months at different temperatures, were tested simultaneously on H5N1-specific IgG or HI capacity. Bars represent the average values of duplicate determinations (deviations were less than 0.2). Immunization groups as in Fig. 1. Storage temperatures: 4°C (white bars), 20°C (gray bars), 40°C (black bars)