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. 2010 Jan 15;12(2):117–129. doi: 10.1208/s12248-009-9164-6

Fig. 8.

Fig. 8

Simulated pharmacokinetic (a) and pharmacodynamic (b) profiles using the final PK/PD model with parameter estimates of the phase IIa dataset and the combined phase IIa and IIb dataset once-daily oral dosing of 0.5 mg tesofensine for 14 weeks