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Trichrome staining for collagen pattern in each group at 3 weeks. In the EGF-treated group, the epidermis is well established. Collagen bundles are mature, organized, and well arranged. The amount of collagen is similar to that of normal stroma. In contrast, an immature, disorganized collagen pattern is noted in the control group and the amount of collagen is smaller than that of normal stroma.
