Mean (±SE) change in plasma glucose (A) and insulin (B) concentrations after intake of a 900-kcal high-fat, high-carbohydrate meal and a 300-kcal drink of orange juice (OJ+meal), glucose (Glu+meal), or water (W+meal) in normal subjects. *,**,#P < 0.05 [repeated-measures ANOVA (RMANOVA)] compared with baseline values after W+meal, Glu+meal, or OJ+meal, respectively; +,$P < 0.05 (2-factor RMANOVA) for comparison between W+meal or Glu+meal and OJ+meal treatments, respectively. P for interaction (treatment × time) = 0.011 for glucose with differences at 1 h between groups; P for interaction (treatment × time) = 0.027 for insulin with differences at 1 h between groups. n = 10 each.