TABLE 3.
Regions exhibiting differential activation during sustained attention1
| Talairach coordinates |
Cluster extent (voxels) | |||
| Brain region (Brodmann's area) | x | y | z | |
| mm | ||||
| Placebo versus low dose | ||||
| DHA > placebo | ||||
| Right inferior frontal gyrus (BA9) | 44 | −3 | 26 | 445 |
| Right precentral gyrus (BA6) | 36 | −10 | 30 | |
| Placebo > DHA | ||||
| Right occipital lobe, lingual gyrus (BA17) | 14 | −87 | 3 | 275 |
| 22 | −89 | −2 | ||
| Left occipital lobe, lingual gyrus (BA17) | −8 | −90 | −4 | |
| Placebo versus high dose | ||||
| DHA > placebo | ||||
| Left superior frontal gyrus (BA9) | −20 | 48 | 36 | 288 |
| −26 | 44 | 29 | ||
| Placebo > DHA | ||||
| Right cerebellum, posterior lobe | 8 | −81 | −21 | 382 |
| Left cerebellum, posterior lobe | −8 | −83 | −23 | |
| −10 | −82 | −35 | ||
| Low dose versus high dose | ||||
| High > low | ||||
| Left parietal lobe (BA43) | −61 | −9 | 17 | 358 |
| Left temporal lobe (BA42) | −59 | −9 | 10 | |
| −51 | −21 | 1 | ||
| Right occipital lobe (BA30) | 26 | −71 | 9 | 278 |
| Right posterior cingulate (BA31) | 26 | −61 | 14 | |
| Right cerebellum, posterior lobe | 8 | −77 | −20 | 1091 |
| 30 | −63 | −20 | ||
| Left cerebellum, posterior lobe | −22 | −69 | −20 | |
DHA, docosahexaenoic acid. Only comparisons that were significant at P < 0.05 (corrected) are included in the table. Larger voxel clusters required more than one set of coordinates.