Table 1.
The expression of target genes of various functions in regions/cells of the endometrium that may be regulated by paracrine factors from the conceptus.
| ENDOMETRIUM | CONCEPTUS | ||
|---|---|---|---|
| TARGET GENE | SOURCE | PARACRINE FACTOR | SOURCE |
| Barrier Function | |||
| Tjp1 | PDZ | ? | Trophoblast/Ectoplacental cone? |
| Interferon-regulated | |||
| Irf8 | ? | ? | ? |
| Ifi202b | ? | ? | ? |
| Iigp | ? | ? | ? |
| Ifi27/Isg12 | ? | ? | ? |
| Isg15 | Decidua | Type I INTERFERON? | Giant Cells |
| Rtp4/Iarp | ? | ? | ? |
| Tissue Growth/Remodeling | |||
| Cst3 | Decidua | ? | ? |
| Bmp2 | Decidua | ? | ? |
| Bmp7 | Decidua | ? | ? |
| Fstl3 | Decidua | ? | ? |
| Htra1 | Decidua | ? | ? |
| Htra2 | Decidua | ? | ? |
| Mmp9 | Decidua | ? | Trophoblast MMP9 |
| Timp3 | Decidua | ? | ? |
| Upa | Decidua | ? | ? |
| Immune Cell Regulation/Function | |||
| GzmE | uNK? | ? | ? |
| Gzmf | uNK? | ? | ? |
| Nkg7 | uNK? | ? | ? |
| Perforin | uNK | ? | ? |
| Prl4a1 | uNK? | ? | ? |
| Prl8a2 | Decidua | ? | ? |
| Spp1 | uNK | ? | ? |
| Vascular Changes | |||
| Angpt1 | ? | ? | ? |
| Angpt2 | Decidua | ? | ? |
| Fgfr1 | ? | ? | ? |
| Procr | Decidua | ? | ? |
| ? | endothelial? | Proliferins | Trophoblast |
| Unknown Function? | |||
| Pglyrp1 | ? | ? | ? |
| Prlpb | Decidua | ? | ? |