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. 2010 Jan 12;59(4):1016–1025. doi: 10.2337/db09-0858

FIG. 4.

FIG. 4.

UAG induces CAC and EPC mobilization. A: Percentage of CACs and EPCs recovered after 6 h of saline, UAG, or AG treatment: (N) healthy donors and (D) diabetic patients (*P < 0.05, diabetic patients vs. healthy donors, #P < 0.05 saline vs. UAG infusion). B: Senescence was evaluated on CACs and EPCs recovered as described in A and expressed as the percentage of SA-β-gal–positive cells (*P < 0.05, diabetic patients vs. healthy donors, #P < 0.05 saline vs. UAG infusion). C: Percentage of EPCs recovered from wild-type or ob/ob mice infused for 12 h with saline, UAG, or AG (*P < 0.05 WT UAG-infused vs. ob/ob UAG-infused mice). D: Senescence was evaluated on murine EPCs treated as described in C and expressed as the percentage of SA-β-gal–positive cells (*P < 0.05, WT vs. ob/ob mice, #P < 0.05 saline vs. UAG infusion). All data are the mean ± SD obtained by three individual investigators.