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. 2010 Jan 26;59(4):1082–1091. doi: 10.2337/db09-1299

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© 2010 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 4. — Enzymatic activities of mitochondrial respiratory chain and citrate synthase activity are decreased in isolated mitochondria from lumbar DRG of STZ-diabetic rats. Enzymatic activity of complex I was assessed as rotenone-sensitive portion of NADH-cytochrome c reductase (NCCR) (n = 5) (A), cytochrome c oxidase (n = 6–7) (B), and citrate synthase (n = 5) (C) and was measured as described in research design and methods. Values are means ± SD, n = as indicated. *P < 0.05 vs. control (Ctrl) (unpaired Student's t test). Db, diabetic.