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Recordings of fura-2 fluorescence in human monocytes. A: OAG-induced calcium influx was measured under control conditions (5.6 mmol/l d-glucose, ○) and in the presence of high glucose (30 mmol/l d-glucose) without (■) and with (▲) TMP (100 μmol/l). B: Summary data showing intracellular calcium levels after treatment of monocytes with high d-glucose for 4 h (control) stimulated with ONOO in the absence and presence of the membrane-permeable TRPC blocker, 2-APB. **P < 0.01.
