Table I.
Genotypes (%) | Genotypic P- value |
Alleles (%) |
Allelic P-valued | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Marker | Marker ID (dbSNP) |
Alleles (major) |
Group | A1/A1 | A1/A2 | A2/A2 | All | M | F | A1 | A2 | All | M | F |
1 | rs2253206 | A/G (G) |
Cases | 25.4 | 53.0 | 21.6 | 0.35 | 0.082a | 0.55 | 51.9 | 48.1 | 0.19 | 0.026a | 0.68 |
Controls | 32.1 | 49.2 | 18.7 | 56.7 | 43.3 | |||||||||
2 | rs2709356 | C/T (C) | Cases | 63.6 | 31.0 | 5.4 | 0.27 | 0.79 | 0.25 | 79.1 | 20.9 | 0.26 | 0.68 | 0.23 |
Controls | 67.0 | 30.8 | 2.2 | 82.4 | 17.6 | |||||||||
3 | rs11904814 | G/T (T) | Cases | 45.7 | 45.7 | 8.6 | 0.17 | 0.22 | 0.33 | 68.5 | 31.5 | 0.12 | 0.082a | 0.68 |
Controls | 55.3 | 36.7 | 8.0 | 73.7 | 26.3 | |||||||||
4 | rs6740584 | C/T (T) | Cases | 31.0 | 49.2 | 19.8 | 0.078a | 0.19 | 0.25 | 55.6 | 44.4 | 0.023a | 0.085a | 0.14 |
Controls | 22.5 | 49.7 | 27.8 | 47.3 | 52.7 | |||||||||
5 | rs17811997 | C/G (G) |
Cases | 86.2 | 13.3 | 0.5 | 0.35 | 0.78 | 0.17 | 92.8 | 7.2 | 0.18 | 0.79 | 0.093a |
Controls | 80.7 | 18.8 | 0.5 | 90.0 | 10.0 | |||||||||
6 | rs13029936 | C/T (C) | Cases | 65.2 | 30.4 | 4.4 | 0.83 | 0.79 | 0.89 | 80.4 | 19.6 | 0.90 | 0.80 | 0.65 |
Controls | 64.9 | 31.9 | 3.2 | 80.8 | 19.2 | |||||||||
7 | rs1806584 | A/G (A) | Cases | 64.0 | 30.1 | 5.9 | 0.18 | 0.53 | 0.26 | 79.0 | 21.0 | 0.37 | 0.76 | 0.32 |
Controls | 65.4 | 32.4 | 2.2 | 81.6 | 18.4 | |||||||||
8 | rs2551941 | A/T (T) | Cases | 39.8 | 48.9 | 11.3 | 0.034a | 0.028a | 0.62 | 64.3 | 35.7 | 0.022a | 0.019a | 0.40 |
Controls | 53.2 | 37.6 | 9.4 | 72.0 | 28.0 |
P-values that met the stage 1 screening threshold P < 0.1.