Table 3.

Correlations between CSF and Plasma Tryptophan, Kynurenine and Kynurenine Metabolites

	CSF TRP (μM)	CSF KYN (nM)	CSF QUIN (nM)
Plasma TRP (uM)	0.14	−0.46*†	−0.26
Plasma KYN (nM)	0.14	0.53**†	0.71***†
Plasma QUIN (nM)	0.32	0.46*†	0.72***†

TRP: L-tryptophan; KYN: L-kynurenine; QUIN: quinolinic acid; n=25-27

Values reported as Spearman's rho

^*−p<0.05

^**−p<0.01

^***−p<0.001

^†−p<0.05 after controlling for multiple comparisons (Holm-Bonferroni method)