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DNA sequencing analysis for the cardiac sodium channel (SCN5A). A: study of normal control individual. B: genetic study of case 1 revealed a novel mutation comprised of a G to T base substitution at nucleotide position 4035 that led to replacement of tryptophan by cysteine at codon 1345. C: DNA sequencing analysis of the mother in case 1. The same SCN1A gene mutation as in case 1 was found in the genetic study of the mother. DNA: deoxyribonucleic acid.
