Table 2.
Adjusted mean values of baseline SF-36 dimensions according to glucose tolerance status at 5 years: the AusDiab study
| SF-36 dimension and diabetes status | Model 1* | P | Model 2† | P | Model 3‡ | P |
|---|---|---|---|---|---|---|
| Physical functioning | ||||||
| NGT 1999 and 2005 | 86.5 ± 0.3 | Ref | 86.2 ± 0.3 | Ref | 79.7 ± 0.7 | Ref |
| Incident IFG | 83.0 ± 1.4 | 0.010 | 85.1 ± 1.3 | 0.424 | 78.5 ± 1.5 | 0.349 |
| Incident IGT | 82.7 ± 1.0 | <0.001 | 84.2 ± 1.1 | 0.048 | 78.1 ± 1.2 | 0.087 |
| Incident newly diagnosed diabetes | 78.2 ± 1.1 | <0.001 | 81.1 ± 1.1 | <0.001 | 75.6 ± 1.2 | <0.001 |
| Role limitation physical | ||||||
| NGT 1999 and 2005 | 84.8 ± 0.5 | Ref | 84.6 ± 0.5 | Ref | 76.8 ± 1.4 | Ref |
| Incident IFG | 78.5 ± 2.6 | 0.017 | 79.7 ± 2.6 | 0.066 | 71.8 ± 2.9 | 0.057 |
| Incident IGT | 80.5 ± 1.9 | 0.031 | 81.3 ± 1.9 | 0.099 | 73.9 ± 2.3 | 0.141 |
| Incident newly diagnosed diabetes | 77.0 ± 2.2 | <0.001 | 78.6 ± 2.2 | 0.007 | 71.8 ± 2.4 | 0.027 |
| Bodily pain | ||||||
| NGT 1999 and 2005 | 76.8 ± 0.3 | Ref | 76.6 ± 0.3 | Ref | 75.6 ± 1.0 | Ref |
| Incident IFG | 69.9 ± 1.8 | <0.001 | 71.4 ± 1.8 | 0.005 | 67.3 ± 2.0 | 0.004 |
| Incident IGT | 71.6 ± 1.3 | <0.001 | 72.6 ± 1.3 | 0.004 | 68.8 ± 1.6 | 0.006 |
| Incident newly diagnosed diabetes | 70.3 ± 1.5 | <0.001 | 72.2 ± 1.5 | 0.005 | 68.8 ± 1.7 | 0.015 |
| General health | ||||||
| NGT 1999 and 2005 | 73.5 ± 0.3 | Ref | 73.3 ± 0.3 | Ref | 65.2 ± 0.8 | Ref |
| Incident IFG | 71.7 ± 1.5 | 0.234 | 73.2 ± 1.5 | 0.953 | 64.9 ± 1.6 | 0.819 |
| Incident IGT | 66.3 ± 1.2 | <0.001 | 67.4 ± 1.1 | <0.001 | 59.7 ± 1.3 | <0.001 |
| Incident newly diagnosed diabetes | 65.6 ± 1.5 | <0.001 | 68.8 ± 1.5 | <0.001 | 60.9 ± 1.4 | 0.001 |
| Vitality | ||||||
| NGT 1999 and 2005 | 64.4 ± 0.3 | Ref | 64.3 ± 0.3 | Ref | 59.7 ± 0.9 | Ref |
| Incident IFG | 62.8 ± 1.6 | 0.335 | 64.0 ± 1.6 | 0.881 | 59.3 ± 1.8 | 0.814 |
| Incident IGT | 60.4 ± 1.2 | 0.001 | 61.2 ± 1.2 | 0.012 | 56.8 ± 1.4 | 0.020 |
| Incident newly diagnosed diabetes | 59.4 ± 1.4 | <0.001 | 60.9 ± 1.4 | 0.017 | 57.1 ± 1.5 | 0.061 |
| Social functioning | ||||||
| NGT 1999 and 2005 | 89.5 ± 0.3 | Ref | 89.4 ± 0.3 | Ref | 86.1 ± 0.8 | Ref |
| Incident IFG | 87.0 ± 1.5 | 0.105 | 87.5 ± 1.5 | 0.229 | 84.1 ± 1.7 | 0.217 |
| Incident IGT | 87.0 ± 1.1 | 0.035 | 87.4 ± 1.1 | 0.078 | 84.1 ± 1.4 | 0.099 |
| Incident newly diagnosed diabetes | 83.8 ± 1.3 | <0.001 | 84.5 ± 1.3 | <0.001 | 81.5 ± 1.5 | 0.001 |
| Role-emotional | ||||||
| NGT 1999 and 2005 | 86.5 ± 0.5 | Ref | 86.5 ± 0.5 | Ref | 84.2 ± 1.4 | Ref |
| Incident IFG | 83.0 ± 2.5 | 0.153 | 83.8 ± 2.5 | 0.294 | 81.5 ± 2.8 | 0.280 |
| Incident IGT | 83.7 ± 1.8 | 0.128 | 84.3 ± 1.8 | 0.243 | 82.1 ± 2.2 | 0.261 |
| Incident newly diagnosed diabetes | 79.8 ± 2.1 | 0.001 | 80.8 ± 2.1 | 0.008 | 78.9 ± 2.4 | 0.014 |
| Mental health | ||||||
| NGT 1999 and 2005 | 77.3 ± 0.3 | Ref | 77.2 ± 0.3 | Ref | 75.8 ± 0.7 | Ref |
| Incident IFG | 75.7 ± 1.4 | 0.243 | 75.9 ± 1.4 | 0.356 | 74.4 ± 1.5 | 0.326 |
| Incident IGT | 74.2 ± 1.0 | 0.003 | 74.4 ± 1.0 | 0.007 | 73.1 ± 1.2 | 0.009 |
| Incident newly diagnosed diabetes | 74.3 ± 1.1 | 0.011 | 74.7 ± 1.1 | 0.028 | 73.5 ± 1.3 | 0.051 |
Data are marginal mean ± SEM.
*Model 1: SF-36 dimensions adjusted for diabetes status, age, and sex.
†Model 2: SF-36 dimensions adjusted for model 1 and BMI, systolic blood pressure and total cholesterol.
‡Model 3: SF-36 dimensions adjusted for model 2 and smoking, known cardiovascular disease and medication for hypertension or a lipid abnormality. Ref, referent.