Table 1.
Clinical and laboratory characteristics
| Control | Type 2 diabetes | P | |
|---|---|---|---|
| n | 23 | 23 | |
| Sex (M/F) | 11/12 | 9/16 | |
| Age (years) | 46 ± 12 | 51 ± 10 | NS |
| BMI (kg/m2) | 25 ± 7 | 34 ± 9 | 0.001 |
| Fasting glucose (mmol/l) | 4.9 ± 0.5 | 8.9 ± 3.1 | 0.0001 |
| Fasting insulin (pmol/l) | 79 ± 17 | 190 ± 120 | 0.018 |
| HOMA-IR | 1.5 ± 0.4 | 3.7 ± 1.8 | 0.001 |
| Fasting FFAs (mEq/l) | 0.3 ± 0.2 | 0.9 ± 0.2 | 0.0001 |
| A1C (%) | 5.2 ± 0.2 | 8 ± 2.1 | 0.05 |
| C-peptide (ng/ml) | 1.2 ± 1 | 2.5 ± 0.6 | 0.001 |
| C-reactive peptide (mg/l) | 2.9 ± 4 | 4.7 ± 4 | 0.002 |
| Total cholesterol (mg/dl) | 184 ± 36 | 190 ± 36 | NS |
| LDL cholesterol (mg/dl) | 115 ± 26 | 120 ± 29 | NS |
| HDL cholesterol (mg/dl) | 50 ± 11 | 39 ± 15 | 0.3 |
| Triglycerides (mg/dl) | 100 ± 62 | 145 ± 67 | 0.45 |
| CML (ng/ml) | 1.9 ± 1.1 | 5.4 ± 3.1 | 0.001 |
Data are means ± SD. P values correspond to the differences between control and type 2 diabetes.