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. Author manuscript; available in PMC: 2010 Mar 25.
Published in final edited form as: J Am Chem Soc. 2009 Jul 1;131(25):8742–8743. doi: 10.1021/ja9025566

Table 1.

Kinetic Parameters for Turnover of Substrates by AmpD at pH 7.0

graphic file with name nihms187488u1.jpg
kcat (s−1) Km (μM) kcat/Km (M−1 s−1)
114 0.4 ± 0.1 1760 ± 210 (2.3 ± 0.1) × 102
2a 25 ± 2.0 360 ± 10 (6.9 ± 0.4) × 104
2c 11 ± 1 500 ± 60 (2.2 ± 0.3) × 104