Table 2.
Multivariate adjusted RR and 95% CI for the association between baseline physical activity and endometrial cancer incidence, NIH-AARP Diet and Health Study
| Physical activity | No. cancers | Person-years | RR* | 95% CI | p for trend | RR § | 95% CI | p for trend | RR † | 95% CI | p for trend |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current daily routine activity at work or home | |||||||||||
| Sit without much walking | 104 | 63,656.5 | 1.00 | <.0001 | 1.00 | <.0001 | 1.00 | 0.07 | |||
| Sit but walk fair amount | 389 | 250,987.7 | 0.90 | (0.73, 1.12) | 0.89 | (0.72, 1.11) | 1.09 | (0.87, 1.35) | |||
| Stand/walk a lot without carrying/lifting things | 370 | 292,047.1 | 0.70 | (0.56, 0.87) | 0.68 | (0.55, 0.85) | 0.97 | (0.77, 1.21) | |||
| Lift/carry light loads or climb stairs/hills often | 150 | 130,859.8 | 0.63 | (0.49, 0.81) | 0.62 | (0.48, 0.79) | 0.89 | (0.69, 1.16) | |||
| Heavy work or carry heavy loads | 12 | 12,284.4 | 0.57 | (0.31, 1.03) | 0.59 | (0.32, 1.06) | 0.81 | (0.45, 1.48) | |||
| Vigorous physical activity during typical month in past 12 months | |||||||||||
| Never/Rarely | 292 | 162,322.2 | 1.00 | <.0001 | 1.00 | <.0001 | 1.00 | 0.02 | |||
| 1–3 times/month | 149 | 110,490.4 | 0.78 | (0.64, 0.95) | 0.77 | (0.63, 0.93) | 0.84 | (0.69, 1.02) | |||
| 1–2 times/week | 221 | 162,617.4 | 0.77 | (0.65, 0.92) | 0.74 | (0.62, 0.89) | 0.88 | (0.73, 1.04) | |||
| 3–4 times/week | 244 | 195,345.4 | 0.70 | (0.59, 0.83) | 0.66 | (0.56, 0.79) | 0.85 | (0.72, 1.02) | |||
| 5+ times/week | 139 | 130,077.2 | 0.60 | (0.49, 0.73) | 0.56 | (0.46, 0.68) | 0.77 | (0.63, 0.95) | |||
| Frequency of participation in physical activities or sports during typical month between ages 15–18 years old | |||||||||||
| Never/Rarely | 169 | 129,904.3 | 1.00 | 0.22 | 1.00 | 0.16 | 1.00 | 0.22 | |||
| 1–3 times/month | 81 | 71,174.2 | 0.89 | (0.68, 1.16) | 0.90 | (0.69, 1.18) | 0.91 | (0.70, 1.19) | |||
| 1–2 times/week | 197 | 137,879.0 | 1.10 | (0.90, 1.35) | 1.10 | (0.90, 1.35) | 1.13 | (0.92, 1.39) | |||
| 3–4 times/week | 258 | 184,622.4 | 1.06 | (0.88, 1.29) | 1.09 | (0.89, 1.32) | 1.10 | (0.91, 1.34) | |||
| 5+ times/week | 340 | 237,840.6 | 1.09 | (0.90, 1.31) | 1.10 | (0.92, 1.32) | 1.09 | (0.91, 1.31) | |||
Relative risks adjusted for age (continuous)
Relative risks adjusted for age (continuous), race (white vs. other/unknown), smoking status (never, former, current, or unknown), parity (nulliparous, one, two, ≥ three births, or unknown), ever use of oral contraceptives (no, yes, unknown), age at menopause (premenopausal, natural menopause at <45, 45–49, 50–54, or ≥ 55 years of age, or unknown age at menopause), and ever use of hormone therapy (no, yes)
Relative risks additionally adjusted for body mass index (continuous)
Not shown are unknown current daily routine activity (27 cancers and 16,335 person-years), vigorous activity (7 cancers and 5,318 person-years), and activity between the ages of 15–18 years (7 cancers and 4,750 person-years).
CI, confidence interval; RR, relative risk