Table 3.
Multivariate adjusted RR and 95% CI for the association between history of occupational physical activity and endometrial cancer incidence among women who completed the second questionnaire, NIH-AARP Diet and Health Study
| Occupational physical activity | No. cancers | Person- years | RR* | 95% CI | p for trend | RR § | 95% CI | p for trend | RR † | 95% CI | p for trend |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Number of physically demanding jobs | |||||||||||
| None | 525 | 370,721.1 | 1.00 | 0.78 | 1.00 | 0.48 | 1.00 | 0.95 | |||
| 1–2 | 90 | 63,460.0 | 1.03 | (0.82, 1.29) | 1.07 | (0.85, 1.33) | 0.99 | (0.79, 1.23) | |||
| 3–5 | 18 | 13,188.5 | 1.01 | (0.63, 1.62) | 1.09 | (0.68, 1.74) | 0.98 | (0.61, 1.57) | |||
| 6+ | 10 | 6,898.9 | 1.07 | (0.57, 2.00) | 1.14 | (0.61, 2.13) | 1.03 | (0.55, 1.93) | |||
| Number of years with a physically demanding job | |||||||||||
| None or less than 1 year | 548 | 387,002.0 | 1.00 | 0.59 | 1.00 | 0.36 | 1.00 | 0.90 | |||
| 1–2 | 8 | 9,532.9 | 0.62 | (0.31, 1.25) | 0.66 | (0.33, 1.32) | 0.60 | (0.30, 1.20) | |||
| 3–5 | 24 | 12,877.6 | 1.38 | (0.92, 2.08) | 1.47 | (0.97, 2.21) | 1.34 | (0.89, 2.02) | |||
| 6–9 | 9 | 10,146.5 | 0.66 | (0.34, 1.28) | 0.69 | (0.36, 1.33) | 0.63 | (0.33, 1.23) | |||
| 10+ | 54 | 34,800.6 | 1.12 | (0.84, 1.48) | 1.17 | (0.88, 1.54) | 1.06 | (0.80, 1.40) | |||
| Number of years walked or biked to work most days | |||||||||||
| None or less than 1 year | 560 | 395,140.9 | 1.00 | 0.89 | 1.00 | 0.62 | 1.00 | 0.68 | |||
| 1–2 | 31 | 17,599.2 | 1.26 | (0.88, 1.80) | 1.27 | (0.88, 1.82) | 1.23 | (0.86, 1.76) | |||
| 3–5 | 25 | 19,280.8 | 0.91 | (0.61, 1.36) | 0.88 | (0.59, 1.32) | 0.88 | (0.59, 1.31) | |||
| 6–9 | 18 | 8,009.2 | 1.55 | (0.97, 2.48) | 1.50 | (0.94, 2.40) | 1.54 | (0.96, 2.46) | |||
| 10+ | 13 | 12,625.6 | 0.70 | (0.40, 1.21) | 0.65 | (0.37, 1.12) | 0.66 | (0.38, 1.15) | |||
Relative risks adjusted for age (continuous)
Relative risks adjusted for age (continuous), race (white vs. other/unknown), smoking status (never, former, current, or unknown), parity (nulliparous, one, two, ≥ three births, or unknown), ever use of oral contraceptives (no, yes, unknown), age at menopause (premenopausal, natural menopause at <45, 45–49, 50–54, or ≥ 55 years of age, or unknown age at menopause), and hormone therapy formulation (never used, ET use, EPT use, or unknown HT use)
Relative risks additionally adjusted for body mass index (continuous)
Not shown are unknown number of physically demanding jobs (7 cancers and 3,084 person-years), number of years with a physically demanding job (7 cancers and 2,993 person-years), and number of years walked or biked to work (3 cancers and 4,697 person-years).
CI, confidence interval; RR, relative risk