Table 1.
Nucleotide differences found in the Orth and Washington B clones based on partial sequencing of the Orth and Washington B genomes. Sequence positions are referenced to the H. CRPV sequence. Frameshifts and amino acid changes are noted.
| n.t. position | Strain | Location | AA change? |
|---|---|---|---|
| 394 A>C | Orth | E6 and E8 | Thr to Pro in E6 No change in E8 |
| 569 C>A | Wash. B | E6 | Ser to Tyr |
| 7432 T>C | Orth | URR | n.a. |
| 7475C>T | Orth | URR | n.a. |
| 7486 T>C | Orth | URR | n.a. |
| 7609 A | Missing in Orth | URR | n.a. |
| 16 G>A | Wash. B | URR | n.a. |
| 33 G>A | Wash. B | URR | n.a. |
| Between 58, 59 G | Insertion ; Wash. B | URR | n.a. |
| 67 G>T | Wash. B | URR | n.a. |
| 69 A>T | Wash. B | URR | n.a. |
| 75 G>A | Wash. B | URR | n.a. |
| 79 G>C | Wash. B | URR | n.a. |
| 94 G>A | Wash. B | URR | n.a. |
| 4336-8 del TTT | Orth | E5 | del Phe |
| 4336-7 del TT | Wash. B | E5 | frameshift |
| Between 4362, 4363 add ACA |
Orth | E5 | add His |
| 4372-3 del AC | Orth | E5 | frameshift |
| 4421 T>C | Orth | E5 | within the frameshift |