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. Author manuscript; available in PMC: 2010 Mar 25.
Published in final edited form as: J Infect Dis. 2008 Nov 1;198(9):1407–1414. doi: 10.1086/592222

Figure 5.

Figure 5

Effect of eukaryotic translation initiation factor 5A (eIF5A) small interference RNA (siRNA) on lipopolysaccharide (LPS)–induced serum concentrations of tumor necrosis factor (TNF)–α and interleukin (IL)–6. A, TNF-α concentrations in mice injected intraperitoneally with 50 µg of control or eIF5A siRNA. After 24 h, 75 µg of LPS was given intranasally, and, 4 h later, blood samples were obtained for determination of serum concentrations of TNF-α. Data are mean ± SE. n = 5 mice in each group. B, IL-6 concentrations in mice pretreated intraperitoneally for 24 h with 50 µg of control or eIF5A siRNA. A total of 75 µg of LPS was given intranasally, and, after 4 h, blood samples were obtained for determination of serum concentrations of IL-6. Data are mean ± SE. n = 5 mice in each group.