Table 2.

Genomic organization of exons encoding rat NAVR/AVR

Exon Number
NAVR	AVR	Intron 3′ Seq	Exon Termini	Intron 5′ Seq	Exon Size, bp	Intron Size, bp	Functional Domain in Exon
1			From 1st (*), 2nd (**), 3rd (***)    initiator seq (Fig. 1)	85*/490**/589***			NAVR +1
From +1
1				gtgagt	29b	535	Initiating M
From aa1			~GCTCCAG
2		cccag	CTCGGAG ~CTGCAGA	gtaagc	272	238
3		tccag	GGCTCGG ~GTGTCGG	gtaagt	36	210
4		tacag	AGTACAA ~TGAAGGG	gtgagt	1,753	746	AVP bd/Gs
	1		AGACTTa ~TGAAGGG	gtgagt	1,088	746	AVR +1 initiating M AVP bd/Gs
5	2	tccag	TTCTCAA ~TTCTGAC	gtgagt	93	1,027
6	3	cacag	CTTGTCA ~CACTCAG	gtaagg	171	75
7	4	cacag	GATACAG ~CCCTCAG	gtaaag	168	422	ANG II bd
8	5	tgcag	TCTGACT ~GGTGGGC		834		Poly(A)
mRNA size, bp
3,412*	2,354
3,902**
4,001***

Seq, nucleotide sequence;

^aAVR transcription RNA initiation site determined by rapid amplification of 5′ cDNA ends (5′-RACE);

^bNAVR exon 1 size determined from initiation-methionine consensus sequence; M, methionine; bd, binding domain; G_s, G_s activator domain.