Skip to main content
. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: J Biopharm Stat. 2010 Mar;20(2):193–208. doi: 10.1080/10543400903572704

Table 3.

Simulation results for average variance of rejected hypotheses

π0 ρ m n Proposed Gilbert Tarone
0.1 0.2 10 100 0.49 0.67 0.72
0.2 20 100 0.44 0.44 0.46
0.2 10 1000 1.16 1.95 2.02
0.2 20 1000 0.51 0.63 0.65
0.2 10 10000 1.5 4.86 4.97
0.2 20 10000 0.80 1.79 1.99
0.5 10 100 0.48 0.86 0.87
0.5 20 100 0.45 0.69 0.74
0.5 10 1000 1.35 4.69 6.00
0.5 20 1000 2.02 8.42 9.47
0.5 10 10000 5.68 53 60.5
0.5 20 10000 3.39 54.0 62.58
0.3 0.2 10 100 0.50 0.57 0.60
0.2 20 100 0.33 0.37 0.39
0.2 10 1000 0.80 1.27 1.32
0.2 20 1000 0.55 0.92 0.92
0.2 10 10000 1.62 4.54 3.70
0.2 20 10000 0.86 1.65 1.69
0.5 10 100 0.73 1.8 4.1
0.5 20 100 0.73 1.46 1.51
0.5 10 1000 4.3 12.95 13.89
0.5 20 1000 2.03 11.71 15.09
0.5 10 10000 4.98 88.8 103.76
0.5 20 10000 9.5 100.2 146.73

Note: π0 proportion of true null hypotheses. The number of hypotheses being tested is n, while there are m subjects per group. Proposed represents the procedure outlined in Section 4.1; Gilbert represents the method of Gilbert (2005); Tarone represents the method of Tarone (1990).