Figure 6.—

Eye discs remain small after Osa overexpression and morphogenetic furrow progression is retarded. (A, C, E, and G) Control eye-antennal imaginal discs. (B, D, F, and H) Osa-overexpressing discs. (A and B) Expression of dacapo or (C and D) atonal was detected by in situ hybridization. Following overexpression, the eye part remains smaller than in control discs, and the MF is positioned farther posteriorly and shows a characteristic half-moon shape. (E and F) X-gal reactions vizualized dpp-lacZ. The inset in E shows dpp-lacZ expression in a young third instar control disc. (F) The dpp-lacZ pattern along the MF is partially disrupted. (G and H) The wg-lacZ expression domain is comparable to the control. Pairwise comparisons of control and mutant discs are to scale. Anterior is to the left; dorsal is up.