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. 2010 Apr;24(4):1178–1191. doi: 10.1096/fj.09-139147

Figure 7.

Figure 7.

Expression of transferred NMP leads to partial functional rescue of the rds+/− phenotype. A) Representative scotopic and photopic traces from naked DNA-injected (gray trace) and nanoparticle-injected eyes (black trace) at PI-30. B) Scotopic a-wave (top) and b-wave (middle) amplitudes from eyes injected with MOP-NMP nanoparticles are elevated compared with naked DNA injected eyes after P5 and P22 injection but do not reach levels seen in age-matched WT animals. Photopic b-wave (bottom) amplitudes from eyes injected with MOP-NMP nanoparticles are elevated compared with naked DNA-injected eyes after P5 and P22 injection and meet or exceed levels seen in age-matched WT animals. Amplitudes are means ± se (N values in Table 1). *P < 0.05, §P < 0.05 vs. nanoparticle treatment.