Figure 6.
Adiposity in male and female RetSat−/− and RetSat+/+ mice maintained on an HFD containing 45 kcal % fat. Male and female RetSat−/− or RetSat+/+ mice (3/group) were maintained on normal chow until 2 mo of age, then treated with an HFD for 10 wk. A) At the end of treatment, adiposity was assessed by MRI and expressed as a percentage of total body weight. B) Representative MRI scans showing fat-only volumes reveal increased adipose tissue accumulation in female RetSat−/− mice maintained on the HFD. Values represent means ± sd; n = 3 animals/genotype. *P < 0.05.