Figure 6. The Golgi mini-stacks in BIG1-depleted cells are still coordinated on microtubules.

A: HeLa transfected for indicated siRNA were treated or not with nocodazole (Nz) and stained for giantin and α-tubulin. B: Quantification of Golgi-particles was done as in previous figures. A higher fragmentation of the Golgi can be achieved by treating BIG1-depleted cells with nocodazole, suggesting that the Golgi mini-stacks are still coordinated on microtubules. Asterisks mean p<0.05 as compared to control untreated cells, # means p<0.05 as compared to nocodazole-treated BIG1-deplepted cells.