Table 1. GO Biological Process enrichment of HGU95Av2 compendium eigengenes.
Eigengene | Term ID | Name | # genes | p-value |
1 | GO:0006412 | Translation | 271 | |
GO:0009059 | Macromolecule biosynthetic process | 431 | ||
GO:0006396 | RNA processing | 269 | ||
2 | GO:0000278 | Mitotic cell cycle | 203 | |
GO:0022403 | Cell cycle phase | 223 | ||
GO:0000279 | M phase | 172 | ||
3 | GO:0007155 | Cell adhesion | 494 | |
GO:0006955 | Immune response | 481 | ||
GO:0000902 | Cell morphogenesis | 305 | ||
4 | GO:0042110 | T cell activation | 86 | |
GO:0046649 | Lymphocyte activation | 128 | ||
GO:0045321 | Leukocyte activation | 145 | ||
5 | GO:0022403 | Cell cycle phase | 223 | |
GO:0000278 | Mitotic cell cycle | 203 | ||
GO:0007067 | Mitosis | 131 | ||
10 | GO:0006941 | Striated muscle contraction | 27 | |
GO:0016567 | Protein ubiquitination | 43 | ||
GO:0006936 | Muscle contraction | 130 | ||
20 | GO:0006323 | DNA packaging | 177 | |
GO:0006997 | Nuclear organization and biogenesis | 22 | ||
GO:0006325 | Establishment of chromatin architecture | 171 | ||
50 | GO:0008354 | Germ cell migration | 6 | |
GO:0050764 | Regulation of phagocytosis | 6 | ||
GO:0007067 | Positive regulation of phagocytosis | 6 | ||
200 | GO:0009187 | Cyclic nucleotide metabolic process | 35 | |
GO:0009605 | Response to external stimulus | 424 | ||
GO:0030193 | Regulation of blood coagulation | 11 |
A Kolmogorov-Smirnov (K-S) test was used to evaluate the significance of enrichment. The member genes of each eigengene were ranked by the absolute value of their weights and the K-S test was run on all Biological Process terms. The top three terms with a p-value of .05 or smaller (and fewer than 500 annotated genes) are displayed.