Table 3. Simulation time comparison between detailed and abstracted models.
Simulation timea (hours) | ||||||
Wild-type | fimB knock-outd | fimB overexpressede | ||||
Model | Partialb | Allc | Partial | All | Partial | All |
Detailed | 28.5 | N/A | 17.1 | N/A | 28.8 | N/A |
Abstracted | 1.5 | 2.85 | 0.67 | 1.17 | 2.38 | 4.57 |
aComputational time for 100,000 stochastic simulation runs as well as model abstraction when applicable for each temperature point on a single PC.
bTemperature points at , , and .
cTemperature points at , , , , , , , , , and .
dSystem with no ON-to-OFF activity.
e overproduction by a factor of 2 compared to wild-type.