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. 2010 Mar 23;39(Suppl 1):i88–i101. doi: 10.1093/ije/dyq026

Table 1.

Quality assessment of trials of the evidence for ITNs for preventing malaria deaths in children <5 years old

Quality assessment						Summary findings
				Directness		Intervention		Control
No. of studies	Design	Limitations	Consistency of results	Generalizability to population of interest	Generalizability to intervention of interest	No. of events	Denominator	No. of events	Denominator	Pooled RR (95% CI)
ACCM: high outcome-specific quality
3	CRCT	Not blinded	Consistent, χ² for heterogeneity (2 df) = 1.5	High	High	1412	47 886	1709	48 152	0.82 (0.75–0.90)
Uncomplicated malaria incidence: high outcome-specific quality
4	CRCT	Not blinded	Inconsistent, χ² for heterogeneity (3 df) = 9.39	High	High	543	30 602	1021	29 316	0.49^a (0.44–0.54)
Prevalence of malaria parasite infection: high outcome-specific quality
6	CRCT	Not blinded	Inconsistent, χ² for heterogeneity (6 df) = 83.5	High	High	2183	3921	2665	4093	0.83^a (0.64–0.88)

CRCT, community randomized controlled trial.

^aRandom effects model.