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. Author manuscript; available in PMC: 2010 Mar 26.
Published in final edited form as: J Immunol. 2006 Oct 1;177(7):4257–4261. doi: 10.4049/jimmunol.177.7.4257

FIGURE 1.

FIGURE 1

Time course of early IL-2 expression and signaling in antiviral CD4 cells. Naive Thy1.1+ HA-specific clonotypic CD4 cells were adoptively transferred into vacc-HA-infected Thy1.2+ NT recipients, recovered from spleens at the indicated times and directly stained for IL-2, CD25, and pSTAT5. The percentages of positively expressing clonotypic cells (CD4+Thy1.1+) are indicated. CD25 vs pSTAT5 staining on endogenous (Thy1.1−) CD4 cells is also shown. Noninfected adoptive transfer recipients served as the control.