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. 2010 Apr;38(4):539–544. doi: 10.1124/dmd.109.031351

Fig. 8.

Fig. 8.

Tumor-cell cytotoxicity of CYP3A4-activated MMDX. A, MMDX cytotoxicity. B, incomplete Freund's adjuvant (IFA) cytotoxicity. C, reversal by CYP3A inhibitors. [The figure has been drawn on the basis of the findings in Lu et al., 2009.]