Table 1.

Properties of GAS clinical isolates and effects of GAS exposure on DC phenotype.

	iDC	Group I isolates	Group II isolates	Group III isolates
GAS Phenotype
No. of isolates		6	3	15
HA (fg/CFU)		13.6 ± 7.6	50.2 ± 17.2	4.9 ± 3.0
SLO (HU)		1.8 ± 0.3	21.6 ± 13.2	20.2 ± 5.5
DC Phenotype
CD83 (MFI)	2.3 ± 1.1	10.3 ± 0.4	2.9 ± 0.4	1.8 ± 0.2
HLA-DR (MFI)	14.4 ± 0.7	23.5 ± 1.1	14.3 ± 1.4	7.5 ± 0.4
CD80 (MFI)	18.6 ± 0.3	50.7 ± 5.2	17.1 ± 3.1	3.7 ± 0.4
Hypodiploid DC (%)	5.9 ± 1.1	8.3 ± 0.8	10.5 ± 3.0	58.4 ± 2.0
DC with associated GAS (%)		74.0 ± 6.5	21.8 ± 9.1	90.6 ± 1.0

Note.- iDC = Untreated DC; MFI = Median Fluorescence Intensity; HU = Hemolytic Units. Values reported correspond to group means±SD.