Fig. 6.

Effect of MC on luciferase expression using deletion plasmids. HepG2 cells were transiently transfected with a plasmid containing one of several deletions of the human CYP1A1 promoter (pGL3-1A1) and reported (luciferase) gene was determined, as described under Materials and Methods. Data represent mean ± S.E. of three independent experiments. *, statistically significant differences between MC- and DMSO-treated cells at P < 0.05, as determined by two-way ANOVA.