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. 2010 Apr;333(1):140–151. doi: 10.1124/jpet.109.162271

Fig. 6.

Fig. 6.

Hepatic mRNA and protein expression of Nrf2 and target gene Nqo1 in wild-type and Nrf2-null mice after STZ. A, messenger RNA expression of Nrf2 and Nqo1 were quantified using total hepatic RNA from control and STZ-treated wild-type and Nrf2-null mice on day 10. B, Western immunoblots were performed using the cytosol fraction from control and STZ-treated wild-type and Nrf2-null mice on day 10. Western blot data were quantified. Data were normalized to wild-type controls and presented as mean relative expression ± S.E. Black bars represent wild-type mice, and gray bars represent Nrf2-null mice. Asterisks (∗) represent statistically significant differences (p < 0.05) compared with control mice of that genotype. Daggers (†) represent a statistically significant difference (p < 0.05) between wild-type and Nrf2-null mice with the same treatment.