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. 2010 Apr;333(1):140–151. doi: 10.1124/jpet.109.162271

Fig. 9.

Fig. 9.

Effect of oltipraz on blood glucose levels of wild-type mice after STZ. Blood glucose levels were quantified on days −1, 1, 3, 5, 7, 9, and 10 in wild-type mice treated with citrate buffer or STZ (200 mg/kg i.p.) on day 0 and either corn oil (5 ml/kg) or oltipraz (150 mg/kg i.p.). Corn oil or oltipraz was administered on days 0.5 (12 h after STZ), 2, 4, 6, and 8. Day −1 blood glucose levels represent pretreatment values. Blood glucose levels were similar between citrate vehicle-only (148–184 mg/dl) and oltipraz-only (129–160 mg/dl) mice of both genotypes (data not shown). Data are presented as mean ± S.E. (n = 4). Asterisks (∗) represent statistically significant differences (p < 0.05) compared with control mice of that genotype. Daggers (†) represent a statistically significant difference (p < 0.05) from STZ-only treatment.