Figure 5. Effect of chronic (2 weeks) ACE inhibition (Captopril, 150 mg/kg/d) on (A) chymase activity and (B) Ang II in the LV ISF on conscious WT mice concurrently treated with vehicle, chymase inhibitor (CI-A, 200 mg/kg, b.i.d.) (CI), or bradykinin B2 receptor antagonist (Hoe-140, 0.5 mg/kg/d).
Values are mean ± SEM. In each group, values in parentheses represent n. *P < 0.05; ***P < 0.001.