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. 2010 Mar 8;120(4):1298–1309. doi: 10.1172/JCI39566

Figure 9. Clinical associations between miR-31 expression profiles and those of its target genes, LATS2 and PPP2R2A, were explored as described in Methods.

Figure 9

(A) Associations between cyclin E immunohistochemical expression and miR-31 levels were significant. (B) Augmented miR-31 expression was more frequent in malignant as compared with normal lung tissues. (C) LATS2 and PPP2R2A were significantly downregulated in lung cancers as compared with adjacent normal lung tissues. “Other” indicates lung cancer histopathologies. Error bars indicate SEM in A and SD in B and C. *P < 0.05, ***P < 0.0001.