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IgM (A) and IgG (B) responses to NP were measured by ELISA on days 0, 7, 14, and 54 after immunization of NOD (n = 6) and NOD.DO (n = 6) mice with NP-CGG in alum. Each symbol represents an individual mouse, and horizontal bars represent the mean values for each group. P values were computed using 2-tailed, unpaired Student’s t test and showed no significance differences between NOD and NOD.DO mice.
