Table 3.

Average COAT scores: parameter estimates with their standard errors and tests of significance

Parameter	Estimate	SE	t value	df	Pvalue
Intercept (100 mg)	4.542	0.705	6.442	13.699	0.000
Treatment (1000 mg)	0.263	0.923	0.285	13.698	0.780
Time 0–21 (days)	–0.036	0.018	–2.014	108.787	0.047
Time 21–84	–0.001	0.005	–0.227	87.490	0.821
Time 0–21 by treatment (1000 mg)	–0.027	0.023	–1.166	108.725	0.246
Time 21–84 by treatment (1000 mg)	–0.017	0.007	–2.539	87.311	0.013
Random: Subject level variance	2.078	0.949	2.190		0.029
Daily variance AR1	0.739	0.059	12.528		0.000
rho AR1	0.680	0.025	26.749		0.000

Abbreviation: SE, standard error.